Physical and chemical properties and safety application elements of polyethylene glycol PEG

Polyethylene glycol PEG is a polymer prepared by stepwise addition reaction of ethylene oxide with water or ethylene glycol as raw material. It is a white paraffin-like flake or powder solid, odorless or with weak odor. It is non-toxic, non-irritating, has good water solubility, and has good compatibility with many organic components.

Physical and chemical properties of polyethylene glycol PEG

Polyethylene glycol PEG is a colorless or slightly yellow liquid or semi-solid easily soluble in water, with low toxicity, tasteless, odorless, non-volatile, non-burning characteristics, liquid at room temperature. The main characteristic of PEG is its oxidation chemical property on the molecular chain, which makes it soluble, stable and biocompatible.

Polyethylene glycol PEG is soluble in most solvents, including water, methanol, ethanol, ether, dichloromethane, etc. At the same time, PEG also has certain surface activity, which can cooperate with drugs or biological macromolecules to improve the water solubility and bioavailability of drugs.

Polyethylene glycol is non-toxic, non-irritating, has good water solubility, and has a good compatibility with many organic components. They have excellent lubricity, moisture retention, dispersion, adhesive, antistatic agent and softener.

Three safety application points of polyethylene glycol PEG

1, PEG toxicity is low, will not cause obvious harm to the human body, but high concentrations of PEG can induce urticaria, skin allergy and other allergic reactions, there is a risk of sensitization to some people.

2, PEG is a flammable substance, the compound will release toxic gases and harmful substances when burning, the use of Mars and high temperature should be avoided.

3, polyethylene glycol PEG will react with other drugs or chemicals, and should be avoided for substances that cannot be dissolved in the compound.